Tuesday 20 May 2014

Primary antibodies


Primary antibody are antibodies raised against an antigenic target of interest, including protein, peptide, carbohydrate, or other small molecules. Primary antibodies can be monoclonal antibodies or polyclonal antibodies that recognize and bind with high affinity and specificity to unique epitopes across a broad spectrum of biomolecules. Primary antibodies are useful not only to detect specific biomolecules but also to measure changes in their level and specificity of modification by processes such as phosphorylation, methylation or glycosylation. Primary antibodies are useful tools in many scientific disciplines, such as analytical cytology, cell biology and molecular biology. A range of analytical technologies are developed in which primary antibodies are used. A primary antibody can also be very useful for the detection of biomarkers for diseases such as cancer, diabetes, Parkinson′s and Alzheimer′s disease and they are used for the study of ADME & multi-drug resistance of therapeutic agents.

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