Primary antibody are antibodies raised against an antigenic
target of interest, including protein, peptide, carbohydrate, or other small
molecules. Primary antibodies can be monoclonal antibodies or polyclonal
antibodies that recognize and bind with high affinity and specificity to unique
epitopes across a broad spectrum of biomolecules. Primary antibodies are useful
not only to detect specific biomolecules but also to measure changes in their
level and specificity of modification by processes such as phosphorylation,
methylation or glycosylation. Primary
antibodies are useful tools in many scientific disciplines, such as
analytical cytology, cell biology and molecular biology. A range of analytical
technologies are developed in which primary antibodies are used. A primary
antibody can also be very useful for the detection of biomarkers for diseases
such as cancer, diabetes, Parkinson′s and Alzheimer′s disease and they are used
for the study of ADME & multi-drug resistance of therapeutic agents.
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